← Latest venture news

Aisthesis Medical raises £900k pre-seed led by Twin Path Ventures to transform sepsis prediction with AI clinical decisioning

🔎
Aisthesis Medical
🧑
Ioannis Gkouzionis; Vasilis Dimakopoulos; Sotiris Liliopoulos
💰
£900k
🌎
London, United Kingdom
Oct 1, 2025

Aisthesis Medical, a UK-based healthtech startup developing hospital-grade AI clinical decision support software, today announced the successful closing of a £900k pre-seed funding round led by Twin Path Ventures with participation from TECS Capital. The funding will accelerate the development and regulatory clearance of VIOSync SPI, an AI-powered platform that predicts in-hospital sepsis development within the next 48 hours.

Sepsis is one of the world’s most urgent healthcare challenges, causing over 11 million deaths each year and costing healthcare systems billions. Early detection and timely intervention are critical, yet frontline clinicians often lack the tools to identify the onset of sepsis before deterioration occurs.

VIOSync Sepsis Prediction Index (SPI) addresses this need by securely ingesting multimodal patient data from hospital systems to create a digital twin of the patient’s evolving physiology. Using explainable AI algorithms, the platform predicts the onset of sepsis within 48 hours, providing clinicians with transparent risk drivers and actionable insights to intervene earlier and save lives.

This investment will support Aisthesis Medical’s mission to empower clinicians with trusted, explainable AI tools that prevent life-threatening patient deterioration. Funds will be used to advance CE MDR submission for VIOSync SPI, expand clinical validation studies across leading hospitals in the UK and EU, and strengthen the team ahead of NHS and international pilot deployments.

I’ve lived through sepsis twice. I know how quickly stability becomes a crisis and how much an earlier insight can change the outcome. With VIOSync we’re giving clinicians a trusted, explainable way to predict risk before symptoms emerge, enabling faster decisions and ultimately saving lives. This funding is a strong validation of our mission and will help us accelerate both regulatory approvals and clinical adoption.
Ioannis Gkouzionis, Co-founder & CEO
Sepsis is a silent killer that has long lacked predictive tools clinicians can trust. Aisthesis Medical’s combination of explainable AI, multimodal data integration, and digital twin technology is uniquely positioned to set a new standard in sepsis care. We are proud to back this exceptional team as they take the next steps towards regulatory approval and market launch.
Katie Lockwood, Partner at Twin Path Ventures
Backing Aisthesis Medical as our first investment in TECS Capital II reflects exactly the kind of impact-driven, deep-tech entrepreneurship we stand for. Transforming sepsis prediction with explainable AI goes beyond innovation, representing a life-saving shift in clinical practice. With clinical validation underway in the UK and EU and a disciplined path toward CE MDR approval, we’re proud to support an exceptional founding team in bringing this product to market.
Antonis Ilias, Partner at TECS Capital
POWERED BY
POWERED BY